Charlotte Kopitz Selected Research

BAY-8002

11/2018

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance.

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Charlotte Kopitz Research Topics

Disease

25	Neoplasms (Cancer) 01/2022 - 09/2002
12	Neoplasm Metastasis (Metastasis) 01/2017 - 10/2002
4	T-Cell Lymphoma (Lymphoma, T Cell) 05/2005 - 10/2002
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 11/2004
2	Melanoma (Melanoma, Malignant) 01/2017 - 01/2015
2	Ovarian Neoplasms (Ovarian Cancer) 02/2015 - 09/2002
2	Breast Neoplasms (Breast Cancer) 12/2012 - 06/2011
2	Lymphoma (Lymphomas) 12/2010 - 03/2008
2	Fibrosarcoma 10/2008 - 10/2005
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2019
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017
1	Carcinogenesis 01/2015
1	Mesothelioma 06/2014
1	Adenocarcinoma of Lung 06/2014

Drug/Important Bio-Agent (IBA)

5	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 12/2012 - 09/2002
5	Matrix Metalloproteinases (MMPs)IBA 03/2008 - 10/2002
4	Tissue Inhibitor of Metalloproteinase-1IBA 12/2010 - 11/2004
4	Peptide Hydrolases (Proteases)FDA Link 12/2010 - 10/2003
4	Matrix Metalloproteinase InhibitorsIBA 05/2005 - 10/2002
3	Immunoconjugates (Immunoconjugate)IBA 01/2017 - 06/2014
3	Serine Proteases (Serine Protease)IBA 06/2011 - 01/2003
3	GelatinasesIBA 03/2008 - 10/2002
2	EnzymesIBA 01/2022 - 01/2015
2	Pharmaceutical PreparationsIBA 01/2022 - 05/2005
2	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 11/2020 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2003
2	6- (4- (diethylamino)- 3- nitrophenyl)- 5- methyl- 4,5- dihydropyridazin- 3(2H)- oneIBA 01/2020 - 11/2019
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2019 - 11/2016
2	1- cyclopropyl- 4- (4- ((5- methyl- 3- (3- (4- (trifluoromethoxy)phenyl)- 1,2,4- oxadiazol- 5- yl)- 1H- pyrazol- 1- yl)methyl)pyridin- 2- yl)piperazineIBA 01/2017 - 01/2015
2	auristatinIBA 01/2017 - 11/2016
2	Small Interfering RNA (siRNA)IBA 02/2015 - 03/2008
2	Messenger RNA (mRNA)IBA 12/2012 - 06/2011
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2010 - 09/2007
2	Plasminogen Activators (Plasminogen Activator)IBA 12/2010 - 10/2008
2	Cystatin CIBA 10/2008 - 10/2005
2	Cysteine Proteases (Cysteine Protease)IBA 10/2008 - 10/2005
2	Cyclic PeptidesIBA 01/2003 - 09/2002
1	Cytotoxins (Cytolysins)IBA 01/2022
1	CamptothecinIBA 01/2022
1	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2022
1	IntegrinsIBA 01/2022
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 11/2019
1	RogaratinibIBA 01/2019
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Monocarboxylic Acid TransportersIBA 11/2018
1	BAY-8002IBA 11/2018
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2017
1	aprutumab ixadotinIBA 11/2016
1	Carboplatin (JM8)FDA LinkGeneric 02/2015
1	PlatinumIBA 02/2015
1	Growth Differentiation Factor 15IBA 02/2015
1	VemurafenibIBA 01/2015
1	Differentiation AntigensIBA 06/2014
1	MesothelinIBA 06/2014
1	anetumab ravtansineIBA 06/2014
1	Extracellular Matrix ProteinsIBA 06/2011
1	matrigelIBA 06/2011
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 03/2008
1	DisintegrinsIBA 09/2007
1	Cysteine (L-Cysteine)FDA Link 10/2005
1	CathepsinsIBA 10/2005
1	PapainIBA 10/2005
1	Cathepsin BIBA 10/2005
1	SB 3CT compoundIBA 05/2005
1	Urokinase Plasminogen Activator ReceptorsIBA 01/2003
1	AntibodiesIBA 01/2003
1	Peptides (Polypeptides)IBA 09/2002

Therapy/Procedure

5	Therapeutics 01/2019 - 01/2003